August 27, 2017

Buprenorphine for the Treatment of Opioid Dependence

Buprenorphine has been available as a prescription opioid in Canada since 2008. It is marketed as Suboxone® by RB Pharmaceuticals in ombination with naloxone in a […]
August 2, 2017

National Guidelines for Medication-Assisted Treatment of Opioid Dependence

The age of first use, route of administration and individual response to drug user are all factors that influence the likelihood of initial drug use progressing […]
July 23, 2017

Methadone and buprenorphine for the management of opioid dependence

1.1Methadone and buprenorphine (oral formulations), using flexible dosing regimens, are recommended as options for maintenance therapy in the management of opioid dependence. 1.2The decision about which drug […]
July 11, 2017

Use of Oxycodone in Pain Management

Oxycodone is widely used to alleviate moderate-to severe acute pain, It is an effective analgesic for many types of pain, and is especially useful for paroxysmal […]
July 9, 2017

Opioid Dependence Treatment and Guidelines

In response to the increased incidence of opioid abuse, the large degree of variance in patterns for prescribing opioids, and the many different medical specialties involved in […]
July 3, 2017

Flexible dosing of Tincture of Opium in the management of opioid

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT In parts of South-East Asia, Tincture of Opium (TOP) is a culturally acceptable alternative to methadone in the treatment […]
June 24, 2017

Substitute Prescribing for Opioid Dependence

Aims and benefits of treatment The aims of prescribing for opioid dependence are to: Reduce or prevent withdrawal symptoms. Provide an opportunity to stabilise drug intake […]
June 24, 2017

Role of buprenorphine in acute postoperative pain

Role of buprenorphine in acute postoperative pain Utilidad de la buprenorfina en el dolor agudo postoperatorio Abstract Nowadays acute postoperative pain persists as a high prevalence […]
June 24, 2017

Community management of opioid overdose

Overview An estimated 69 000 people die each year from opioid overdose. Opioid overdose is easily reversed with the opioid antidote naloxone and with basic life […]
June 24, 2017

Body Composition Changes Associated With Methadone Treatment

Body Composition Changes Associated With Methadone Treatment Background: Methadone is associated with a statistically significant increase in BMI in the first 2 years of treatment. Objectives: […]
June 24, 2017

Patient-reported pathways to opioid use disorders and pain

Patient-reported pathways to opioid use disorders and pain-related barriers to treatment engagement Highlights •Acute pain, chronic pain, and emotional distress play different contributing roles in developing […]
January 8, 2017

Maintenance Therapy with Opium Tincture

Maintenance Therapy with Opium Tincture for Injecting Drug Users; Implications for Prevention from Viral Infections Viral infections such as HIV and HCV have a serious negative […]
January 7, 2017

Genes and Addiction

Susceptibility Does Not Mean Inevitability When scientists look for “addiction genes,” what they are really looking for are biological differences that may make someone more or […]
January 7, 2017

The addicted brain

The addicted brain Drug addiction has been a stubborn problem for thousands of years, but only in the last generation have scientists come to understand clearly […]