Rosuvastatin is a competitive inhibitor of HMG-CoA reductase, also known as a "statin." HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonate, an early rate-limiting step in cholesterol biosynthesis. Rosuvastatin acts primarily in the liver. Decreased hepatic cholesterol concentrations stimulate the upregulation of hepatic low density lipoprotein (LDL) receptors which increases hepatic uptake of LDL. Rosuvastatin also inhibits hepatic synthesis of very low density lipoprotein (VLDL). The overall effect is a decrease in plasma LDL and VLDL. In vitro and in vivo animal studies also demonstrate that rosuvastatin exerts vasculoprotective effects independent of its lipid-lowering properties.


Rosuvastatin is used for Lowering high cholesterol and triglycerides in certain patients.
• It also increases high-density lipoprotein (HDL) ("good") cholesterol levels.
• It is used to slow atherosclerosis (narrowing of the arteries) in patients with high blood cholesterol levels.
• It is used in certain patients to reduce the risk of heart attack or stroke.
• It is also used in certain patients to reduce the need for medical procedures to open blocked heart vessels. It is used along with an appropriate diet.
• In summary rosuvastatin may used for Atherosclerosis, Atherosclerotic Cardiovascular Diseases, Cardiovascular Diseases, Dysbetalipoproteinemia, Familial hyperlipidemia, Heterozygous Familial Hypercholesterolemia, Homozygous Familial Hypercholesterolemia, Hypertriglyceridemias and Mixed hypercholesterolemia


F.C tablet: 10,20mg


The most frequently reported side effects included:
• Headache and dizziness
• Muscle and joint pain
• Abdominal pain
• Asthenia
• Nausea
• Elevated sugar levels
• Memory loss
• Confusion